Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040621 | 0.76 | MAOA (0.47) | — | |
| SCHEMBL7784781 | 0.76 | MCL1 (0.49) | LTA4H | |
| SCHEMBL1780240 | 0.75 | MCL1 (0.46) | CHUK | |
| SCHEMBL27341835 | 0.73 | LOXL2 (0.42) | LOXL2HRH3TAAR1NSD2NEK1 | |
| SCHEMBL15245752 | 0.72 | LOXL2 (0.86) | LOXL2HRH3TAAR1NSD2 | |
| SCHEMBL9219845 | 0.71 | KIF11 (0.56) | — | |
| Hydrochloric Acid SCHEMBL20497332 | 0.71 | LOXL2 (0.83) | LOXL2HRH3TAAR1NSD2 | |
| SCHEMBL27340414 | 0.70 | LOXL2 (0.46) | LOXL2HRH3TAAR1ASIC3NSD2 | |
| Water SCHEMBL5709165 | 0.69 | LOXL2 (1.00) | LOXL2HRH3NSD2ABAT | |
| SCHEMBL297224 | 0.69 | LOXL2 (1.00) | LOXL2HRH3NSD2ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1059723-A | Hete rocyclic derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-03-25 | — | — | CN | disclosed |