Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760069 | 0.89 | ALDH1A1 (0.51) | AGTR1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL5109110 | 0.83 | CES2 (0.55) | ALDH1A1KMT2AMEN1POLBCES2 | |
| SCHEMBL1986403 | 0.82 | CES2 (0.70) | AGTR1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL27788349 | 0.81 | AGTR1 (0.57) | AGTR1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL28320452 | 0.80 | KMT2A (0.53) | AGTR1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL27862161 | 0.78 | TSHR (0.50) | AGTR1ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL14481735 | 0.78 | HTT (0.49) | AGTR1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL5500374 | 0.78 | TP53 (0.67) | AGTR1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL27644904 | 0.77 | MAPT (0.38) | AGTR1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL7406991 | 0.77 | TP53 (0.65) | AGTR1ALDH1A1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149287-A | Process for the preparation of unsaturated amino compounds | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | CN | disclosed |