Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4995662 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL27548059 | 0.85 | TSHR (0.54) | TSHRALDH1A1TDP1KDM4ECYP3A4 | |
| SCHEMBL28775541 | 0.82 | TSHR (0.51) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL643873 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL647368 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL17184346 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL27797779 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL27750330 | 0.76 | TSHR (0.49) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL29959661 | 0.75 | TSHR (0.70) | SMN1; SMN2KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL307312 | 0.75 | TSHR (0.70) | SMN1; SMN2KMT2AMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1181818-C | Method for treating protozoal infections | 阿莱格亨尼健康科学大学 | 2004-12-29 | — | — | CN | disclosed |
| CN-1136451-C | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ��ũҵ��ѧ��˾ | 2004-01-28 | — | — | CN | disclosed |
| CN-1211736-A | Use of certain amides as probes for detection of antitubulin activity and resistance monitoring | ROHM & HAAS (US) | 1999-03-24 | — | — | CN | disclosed |
| CN-1198330-A | Method for treating protozoal infections | ALLEGHENY UNIVERSITY OF THE HE (US) | 1998-11-11 | — | — | CN | disclosed |