Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775541 | 0.87 | TSHR (0.51) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL27883380 | 0.87 | SIRT6 (0.48) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL9304506 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2TSHRKMT2AMEN1CRHBP | |
| SCHEMBL17184346 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL6211358 | 0.84 | SIRT6 (0.46) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL29164229 | 0.83 | PDGFRB (0.43) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL24100415 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL15122867 | 0.83 | SIRT6 (0.45) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA | |
| SCHEMBL24100061 | 0.83 | TDP1 (0.48) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL4995662 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2SIRT6PDGFRBFGFR1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103224460-A | Herbicide containing benzoylpyrazole compound | ISHIHARA SANGYO KAISHA | 2013-07-31 | — | — | CN | disclosed |
| EP-2084136-B1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA (JP) | 2013-03-13 | — | — | EP | disclosed |
| CN-101541755-B | Benzoylpyrazole compounds, process for their production and herbicides containing them | ISHIHARA SANGYO KAISHA | 2012-06-27 | — | — | CN | disclosed |
| US-8119569-B2 | Benzoylpyrazole compounds, process for their production and herbicides containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20100317528-A1 | HERBICIDE CONTAINING BENZOYLPYRAZOLE COMPOUND | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-12-16 | — | — | US | disclosed |
| US-20100075855-A1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-03-25 | — | — | US | disclosed |
| CN-101573035-A | Herbicide containing benzoylpyrazole compound | ISHIHARA SANGYO KAISHA (JP) | 2009-11-04 | — | — | CN | disclosed |
| EP-2103215-A1 | HERBICIDE CONTAINING BENZOYLPYRAZOLE COMPOUND | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-09-23 | — | — | EP | disclosed |
| CN-101541755-A | Benzoylpyrazole compounds, process for their production and herbicides containing them | ISHIHARA SANGYO KAISHA (JP) | 2009-09-23 | — | — | CN | disclosed |
| EP-2084136-A1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008065907-A1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317528-A1 | HERBICIDE CONTAINING BENZOYLPYRAZOLE COMPOUND | HDHD5, HCAR3, CBR3 | SMN1; SMN2 4824/4885SIRT6 777/4885PDGFRB 2195/4885 |
| US-20100075855-A1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | HACL2, HDHD5, CBR3 | SMN1; SMN2 4433/4885SIRT6 2326/4885PDGFRB 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.