Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4995662 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MAPTPDGFRBFGFR1 | |
| SCHEMBL27448441 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTPDGFRBFGFR1 | |
| SCHEMBL28775541 | 0.78 | TSHR (0.51) | SMN1; SMN2ALDH1A1MAPTPDGFRBFGFR1 | |
| SCHEMBL16035002 | 0.78 | HDAC3 (0.38) | SMN1; SMN2ALDH1A1MAPTKDRKMT2A | |
| SCHEMBL9191452 | 0.78 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL27122616 | 0.77 | MAPT (0.45) | SMN1; SMN2MAPTPDGFRBFGFR1PDGFRA | |
| SCHEMBL268658 | 0.77 | TDP1 (0.55) | SMN1; SMN2ALDH1A1MAPTPDGFRBFGFR1 | |
| SCHEMBL13280639 | 0.77 | PDGFRB (0.46) | SMN1; SMN2ALDH1A1MAPTPDGFRBFGFR1 | |
| SCHEMBL17184346 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MAPTPDGFRBFGFR1 | |
| SCHEMBL647368 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MAPTPDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103224460-A | Herbicide containing benzoylpyrazole compound | ISHIHARA SANGYO KAISHA | 2013-07-31 | — | — | CN | disclosed |
| EP-2084136-B1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA (JP) | 2013-03-13 | — | — | EP | disclosed |
| CN-101541755-B | Benzoylpyrazole compounds, process for their production and herbicides containing them | ISHIHARA SANGYO KAISHA | 2012-06-27 | — | — | CN | disclosed |
| US-8119569-B2 | Benzoylpyrazole compounds, process for their production and herbicides containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20100317528-A1 | HERBICIDE CONTAINING BENZOYLPYRAZOLE COMPOUND | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-12-16 | — | — | US | disclosed |
| US-20100075855-A1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-03-25 | — | — | US | disclosed |
| CN-101573035-A | Herbicide containing benzoylpyrazole compound | ISHIHARA SANGYO KAISHA (JP) | 2009-11-04 | — | — | CN | disclosed |
| EP-2103215-A1 | HERBICIDE CONTAINING BENZOYLPYRAZOLE COMPOUND | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-09-23 | — | — | EP | disclosed |
| CN-101541755-A | Benzoylpyrazole compounds, process for their production and herbicides containing them | ISHIHARA SANGYO KAISHA (JP) | 2009-09-23 | — | — | CN | disclosed |
| EP-2084136-A1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008065907-A1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317528-A1 | HERBICIDE CONTAINING BENZOYLPYRAZOLE COMPOUND | HDHD5, HCAR3, CBR3 | SMN1; SMN2 4824/4885ALDH1A1 1571/4885MAPT 4498/4885 |
| US-20100075855-A1 | BENZOYLPYRAZOLE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM | HACL2, HDHD5, CBR3 | SMN1; SMN2 4433/4885ALDH1A1 708/4885MAPT 4680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.