Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26898819 | 0.81 | PRKCI (0.43) | KIF18AHTR2CPRKCIDRD2BRAF | |
| SCHEMBL15945569 | 0.80 | HTR2C (0.54) | SMN1; SMN2ALDH1A1IKBKETBK1HTR2C | |
| SCHEMBL22104134 | 0.77 | HDAC4 (0.43) | SMN1; SMN2HTR2CPRKCITDO2TRIM24 | |
| SCHEMBL20010986 | 0.77 | SLC6A2 (0.44) | IKBKETBK1HTR2CSLC6A4SLC6A3 | |
| SCHEMBL731682 | 0.77 | ALDH1A1 (0.39) | ALDH1A1IKBKETBK1HTR2C | |
| SCHEMBL5730886 | 0.77 | MGLL (0.40) | IKBKETBK1HTR2CDRD2 | |
| SCHEMBL2916071 | 0.77 | HTR2C (0.57) | SMN1; SMN2ALDH1A1HTR2CDRD2 | |
| SCHEMBL5718532 | 0.77 | MGLL (0.40) | SMN1; SMN2ALDH1A1IKBKETBK1HTR2C | |
| SCHEMBL16379014 | 0.76 | KMO (0.49) | SMN1; SMN2ALDH1A1HTR2CPRKCITDO2 | |
| Hydrochloric Acid SCHEMBL27990535 | 0.76 | HDAC4 (0.46) | SMN1; SMN2HTR2CPRKCITDO2TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |