Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28110591 | 0.79 | ESR1 (0.33) | MAPK1TP53NPSR1NPC1MITF | |
| SCHEMBL27830419 | 0.69 | THRB (0.41) | KDM4EL3MBTL1SMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL5532399 | 0.68 | ESR1 (0.34) | HTTMAPK1TP53NPSR1RECQL | |
| SCHEMBL27748090 | 0.67 | NQO1 (0.31) | — | |
| SCHEMBL8464048 | 0.67 | METAP2 (0.39) | KDM4EL3MBTL1SMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL5587536 | 0.67 | ESR1 (0.37) | L3MBTL1RECQLSMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL9766120 | 0.67 | SMN1; SMN2 (0.42) | HTTKDM4ELMNAMAPK1L3MBTL1 | |
| SCHEMBL27510709 | 0.66 | ESR1 (0.38) | HTTMAPK1TP53NPSR1RECQL | |
| SCHEMBL12232722 | 0.66 | NQO1 (0.36) | L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL8444533 | 0.66 | TSHR (0.33) | NPC1SMN1; SMN2THRBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1137271-A | 4-benzoylisoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-12-04 | — | — | CN | disclosed |