Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27830419 | 0.80 | THRB (0.41) | TSHRSMN1; SMN2THRBESR1PKM | |
| SCHEMBL8464048 | 0.78 | METAP2 (0.39) | TSHRSMN1; SMN2THRBESR1PKM | |
| SCHEMBL16291780 | 0.76 | NQO1 (0.38) | TSHRSMN1; SMN2THRB | |
| SCHEMBL9766120 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2ESR1NPC1 | |
| SCHEMBL9804239 | 0.74 | SMN1; SMN2 (0.36) | TSHRSMN1; SMN2THRBESR1PKM | |
| SCHEMBL12232722 | 0.73 | NQO1 (0.36) | TSHRSMN1; SMN2 | |
| SCHEMBL10019884 | 0.72 | NQO1 (0.32) | — | |
| SCHEMBL11441439 | 0.72 | KMT2A (0.32) | SMN1; SMN2 | |
| SCHEMBL5587536 | 0.70 | ESR1 (0.37) | TSHRSMN1; SMN2THRBESR1PKM | |
| SCHEMBL5923943 | 0.69 | TAS1R3 (0.61) | SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636120-B1 | EPOXIDATION PROCESS OF CARBONYL COMPOUNDS USING SULPHONIUM OR SULPHOXONIUM YLIDES AND INTERMEDIATES | ZENECA LTD (GB) | 1999-09-08 | — | — | EP | disclosed |
| US-5750740-A | Process for preparing epoxides from carbonyl compounds using sulphonium or sulphoxonium ylides and intermediates useful therein | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5637727-A | Process for preparing epoxides from carbonyl compounds using sulphonium or sulphoxonium ylides and intermediates useful therein | ZENECA LIMITED (GB) | 1997-06-10 | — | — | US | disclosed |
| EP-0636120-A1 | EPOXIDATION PROCESS OF CARBONYL COMPOUNDS USING SULPHONIUM OR SULPHOXONIUM YLIDES AND INTERMEDIATES | ZENECA LIMITED (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1992014703-A1 | EPOXIDATION PROCESS OF CARBONYL COMPOUNDS USING SULPHONIUM OR SULPHOXONIUM YLIDES AND INTERMEDIATES | ZENECA LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |