Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.87 |
| ▸ | DRD2 | P14416 | 7/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.77 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.71 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.71 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.67 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709168 | 0.93 | DRD2 (1.00) | DRD4DRD2KMT2ASIGMAR1HTR2A | |
| SCHEMBL7218186 | 0.89 | DRD4 (0.86) | DRD4DRD2KMT2ASIGMAR1SLC6A12 | |
| SCHEMBL694949 | 0.88 | SIGMAR1 (0.82) | DRD4DRD2KMT2ASIGMAR1SLC6A12 | |
| SCHEMBL31736417 | 0.87 | MCHR1 (0.77) | DRD4KMT2ASIGMAR1SLC6A12SLC6A13 | |
| SCHEMBL7218037 | 0.87 | SIGMAR1 (1.00) | DRD4DRD2KMT2ASIGMAR1SLC6A12 | |
| SCHEMBL27448907 | 0.87 | KMT2A (1.00) | DRD4DRD2KMT2ASIGMAR1SLC6A12 | |
| SCHEMBL29817958 | 0.84 | PRKAA2 (0.67) | DRD4DRD2KMT2ASIGMAR1SLC6A12 | |
| SCHEMBL61848 | 0.83 | TMEM97 (0.83) | DRD4DRD2KMT2ASIGMAR1SLC6A12 | |
| SCHEMBL17946338 | 0.83 | KMT2A (0.80) | DRD4KMT2ASIGMAR1SLC6A12SLC6A13 | |
| SCHEMBL2388851 | 0.83 | KMT2A (0.74) | DRD4DRD2KMT2ASIGMAR1SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998037064-A1 | BENZAMIDES HAVING DOPAMINE D4 RECEPTOR AFFINITY | HOECHST MARION ROUSSEL, INC. (US) | 1998-08-27 | — | — | WO | claimed |
| WO-1998037064-A1 | BENZAMIDES HAVING DOPAMINE D4 RECEPTOR AFFINITY | HOECHST MARION ROUSSEL, INC. (US) | 1998-08-27 | — | — | WO | disclosed |