Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 18/20 | 0.65 |
| ▸ | MMP13 | P45452 | 17/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | MMP14 | P50281 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12076423 | 0.91 | MMP1 (0.79) | MMP1MMP13MMP2MMP3MMP9 | |
| Hydroxyamine SCHEMBL7514521 | 0.89 | MMP1 (0.76) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6956661 | 0.86 | MMP1 (0.84) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7209172 | 0.86 | MMP1 (0.80) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7214294 | 0.86 | MMP1 (0.80) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL27415619 | 0.86 | MMP1 (0.76) | MMP1MMP13USP2HTTSMN1; SMN2 | |
| SCHEMBL3667056 | 0.84 | MMP1 (0.80) | MMP1MMP13USP2HTTSMN1; SMN2 | |
| SCHEMBL7066058 | 0.84 | USP2 (0.71) | MMP1MMP13USP2HTTSMN1; SMN2 | |
| Hydroxyamine SCHEMBL3874403 | 0.83 | MMP1 (0.77) | MMP1MMP13USP2HTTSMN1; SMN2 | |
| SCHEMBL7066448 | 0.82 | MMP13 (0.62) | MMP1MMP13USP2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1113862-C | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2003-07-09 | — | — | CN | claimed |
| CN-1249743-A | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2000-04-05 | — | — | CN | claimed |
| CN-1113862-C | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2003-07-09 | — | — | CN | disclosed |
| CN-1249743-A | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2000-04-05 | — | — | CN | disclosed |