Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094693 | 0.83 | CYP2A6 (0.35) | KDM4EALDH1A1HPGDTP53MEN1 | |
| SCHEMBL16753038 | 0.75 | THRB (0.49) | KDM4EALDH1A1HPGDTP53MEN1 | |
| SCHEMBL1650809 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3147406 | 0.72 | KDM4E (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28834516 | 0.72 | KDM4E (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| Naphthalene SCHEMBL3296369 | 0.72 | LMNA (0.59) | KDM4EALDH1A1HPGDTP53MEN1 | |
| Naphthalene SCHEMBL30742789 | 0.72 | LMNA (0.59) | KDM4EALDH1A1HPGDTP53MEN1 | |
| Naphthalene SCHEMBL30721503 | 0.72 | LMNA (0.59) | KDM4EALDH1A1HPGDTP53MEN1 | |
| SCHEMBL10370767 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7859850 | 0.71 | KEAP1 (0.46) | KDM4EALDH1A1HPGDTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |