Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451824 | 0.84 | MGLL (0.72) | MGLLMAPTRAB9ANPC1MEN1 | |
| Hydrochloric Acid SCHEMBL7106247 | 0.81 | MGLL (0.67) | MGLLMAPTRAB9ANPC1MEN1 | |
| SCHEMBL27451280 | 0.78 | MAPT (0.66) | MGLLMAPTRAB9ANPC1MEN1 | |
| SCHEMBL31050187 | 0.78 | MAPT (0.66) | MGLLMAPTRAB9ANPC1MEN1 | |
| SCHEMBL27451638 | 0.77 | MAPT (0.64) | MGLLMAPTRAB9ANPC1MEN1 | |
| SCHEMBL27451279 | 0.74 | MAPT (0.58) | MGLLMAPTRAB9ANPC1MEN1 | |
| SCHEMBL27452355 | 0.74 | MAPT (0.63) | MGLLMAPTRAB9ANPC1MEN1 | |
| SCHEMBL27451200 | 0.73 | NPC1 (0.68) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL3580954 | 0.72 | RAB9A (0.65) | MGLLMAPTRAB9ANPC1MEN1 | |
| SCHEMBL27451134 | 0.72 | MAPT (0.65) | MGLLMAPTRAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |