Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 15/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7106247 | 0.97 | MGLL (0.67) | MGLLKDM4ERAB9AMEN1NPC1 | |
| SCHEMBL27451200 | 0.85 | NPC1 (0.68) | KDM4ERAB9AMEN1NPC1KMT2A | |
| SCHEMBL27451419 | 0.84 | MGLL (0.54) | MGLLKDM4ERAB9AMEN1NPC1 | |
| SCHEMBL12727648 | 0.81 | MGLL (0.72) | MGLLKDM4ERAB9AMEN1NPC1 | |
| SCHEMBL7110254 | 0.81 | MGLL (0.72) | MGLLKDM4ERAB9AMEN1NPC1 | |
| SCHEMBL2248424 | 0.81 | RAB9A (0.78) | MGLLKDM4ERAB9AMEN1NPC1 | |
| SCHEMBL7104840 | 0.81 | MGLL (0.72) | MGLLKDM4ERAB9AMEN1NPC1 | |
| SCHEMBL7107437 | 0.80 | FAAH (0.67) | MGLLKDM4ERAB9AMEN1NPC1 | |
| SCHEMBL2243918 | 0.80 | FAAH (0.69) | MGLLKDM4ERAB9AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL7108023 | 0.80 | MGLL (0.70) | MGLLKDM4ERAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |