SCHEMBL27451607

SCHEMBL27451607

O=C(Oc1nccs1)[C@@H]1CCCN1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.36
RBBP9 O75884 1/20 0.35
ELANE P08246 1/20 0.34
EPHX2 P34913 1/20 0.33
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
DPP4 P27487 5/20 0.33
DPP8 Q6V1X1 3/20 0.33
DPP9 Q86TI2 2/20 0.33
SCN4A P35499 1/20 0.33
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
FAP Q12884 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
SCN3A Q9NY46 2/20 0.32
ANPEP P15144 1/20 0.32
SCN9A Q15858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2052250 0.77 RBBP9 (0.43) RBBP9ELANEEPHX2MEN1TSHR
SCHEMBL2053535 0.76 RBBP9 (0.53) RBBP9ELANEEPHX2MEN1TSHR
SCHEMBL7067465 0.75 ALDH1A1 (0.43) ADORA2ARBBP9ELANEEPHX2MEN1
SCHEMBL13475920 0.75 ALDH1A1 (0.43) ADORA2ARBBP9ELANEEPHX2MEN1
SCHEMBL27533384 0.75 ALDH1A1 (0.43) ADORA2ARBBP9ELANEEPHX2MEN1
SCHEMBL3005160 0.72 KDM4E (0.56) ADORA2AEPHX2MEN1TSHRKMT2A
SCHEMBL3122718 0.72 MMP1 (0.40) ELANETSHRKDM4EDPP4DPP8
SCHEMBL3005169 0.72 KDM4E (0.56) ADORA2AEPHX2MEN1TSHRKMT2A
SCHEMBL17394816 0.72 ELANE (0.35) ELANEDPP4DPP8DPP9SCN4A
SCHEMBL7271802 0.72 MMP1 (0.40) ELANETSHRKDM4EDPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112195216-B Method for evaluating antioxidant stress benefit of active compound based on bacterial model 南京航空航天大学 2022-06-07 CN claimed
CN-112195216-B Method for evaluating antioxidant stress benefit of active compound based on bacterial model 南京航空航天大学 2022-06-07 CN disclosed
CN-112195216-A Method for evaluating antioxidant stress benefit of active compound based on bacterial model 南京航空航天大学 2021-01-08 CN disclosed
CN-1136806-A Prolyl endopeptidase inhibitors MERRELL DOW PHARMA (US) 1996-11-27 CN disclosed