Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451351 | 0.81 | RAB9A (0.68) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL27452781 | 0.76 | RAB9A (0.55) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL27452084 | 0.76 | SENP7 (0.59) | RAB9ANPC1MAPTSENP7SMN1; SMN2 | |
| SCHEMBL27452286 | 0.75 | NAMPT (0.55) | RAB9ANPC1MAPTSENP7SMN1; SMN2 | |
| SCHEMBL27453205 | 0.75 | MGLL (0.51) | RAB9ANPC1MAPTSENP7SMN1; SMN2 | |
| SCHEMBL27451123 | 0.75 | RAB9A (0.68) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL27452651 | 0.74 | SENP7 (0.50) | RAB9ANPC1MAPTSENP7SMN1; SMN2 | |
| SCHEMBL27452783 | 0.73 | MGLL (0.49) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL27452289 | 0.73 | NAMPT (0.56) | RAB9ANPC1MAPTSENP7SMN1; SMN2 | |
| SCHEMBL3586298 | 0.73 | APP (0.56) | RAB9ANPC1MAPTSENP7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |