Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 3/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452836 | 0.98 | ALDH1A1 (0.43) | ALDH1A1TSHRSMN1; SMN2LMNAGAA | |
| SCHEMBL27452863 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TSHRSMN1; SMN2KMT2APOLB | |
| SCHEMBL27452584 | 0.86 | POLB (0.42) | ALDH1A1TSHRSMN1; SMN2LMNAGAA | |
| SCHEMBL27452947 | 0.77 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL27452946 | 0.77 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL27452837 | 0.74 | HPGD (0.53) | ALDH1A1TSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL27452781 | 0.73 | RAB9A (0.55) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A | |
| SCHEMBL27452581 | 0.71 | POLB (0.45) | ALDH1A1TSHRSMN1; SMN2LMNAGAA | |
| SCHEMBL27452650 | 0.71 | POLB (0.45) | ALDH1A1TSHRSMN1; SMN2LMNAGAA | |
| SCHEMBL27453122 | 0.70 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |