Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452947 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAKMT2APOLBGAA | |
| SCHEMBL27451894 | 0.84 | LMNA (0.48) | SMN1; SMN2LMNAKMT2APOLBGAA | |
| SCHEMBL27452787 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAKMT2APOLBGAA | |
| SCHEMBL27452786 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAKMT2APOLBGAA | |
| SCHEMBL27452949 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAKMT2APOLBGAA | |
| SCHEMBL27452584 | 0.81 | POLB (0.42) | SMN1; SMN2LMNAKMT2APOLBGAA | |
| SCHEMBL27452788 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAKMT2APOLBGAA | |
| SCHEMBL27452834 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAKMT2APOLBGAA | |
| SCHEMBL27452836 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2LMNAKMT2APOLBGAA | |
| SCHEMBL27452864 | 0.77 | ALDH1A1 (0.43) | SMN1; SMN2LMNAKMT2APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |