Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ILK | Q13418 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453024 | 0.86 | DYRK1A (0.48) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27452720 | 0.83 | RAB9A (0.77) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27451638 | 0.81 | MAPT (0.64) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27451529 | 0.80 | APP (0.43) | RAB9AKDM4EAPPGAAHPGD | |
| SCHEMBL27453018 | 0.79 | PAX8 (0.53) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27452355 | 0.78 | MAPT (0.63) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27451960 | 0.76 | PAX8 (0.54) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27451199 | 0.76 | RAB9A (0.67) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27452146 | 0.76 | NPC1 (0.55) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL27452351 | 0.74 | MAPT (0.77) | RAB9ANPC1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |