Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | GLS | O94925 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11497870 | 0.88 | MMP8 (0.62) | KMT2AMMP8MEN1SRCTSHR | |
| SCHEMBL10608600 | 0.84 | MMP8 (0.57) | KMT2AMMP8GLSALDH1A1MEN1 | |
| SCHEMBL3598733 | 0.83 | KMT2A (0.69) | KMT2AMMP8GLSALDH1A1MEN1 | |
| SCHEMBL10610733 | 0.81 | MMP8 (0.54) | KMT2AMMP8GLSALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL27830689 | 0.81 | KMT2A (0.67) | KMT2AMMP8GLSALDH1A1MEN1 | |
| SCHEMBL2914808 | 0.80 | KMT2A (0.64) | KMT2AMMP8GLSALDH1A1MEN1 | |
| SCHEMBL12561192 | 0.79 | MMP8 (0.51) | KMT2AMMP8GLSMEN1LMNA | |
| SCHEMBL27670577 | 0.79 | KMT2A (0.50) | KMT2AMMP8GLSALDH1A1MEN1 | |
| SCHEMBL28474562 | 0.79 | MMP8 (0.73) | KMT2AMMP8GLSALDH1A1MEN1 | |
| SCHEMBL2227571 | 0.78 | KMT2A (0.62) | KMT2AMMP8GLSALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1131665-A | Piperazine derivatives, medicaments comprising these compounds, their use and processes for their preparation | THOMAE GMBH DR K (DE) | 1996-09-25 | — | — | CN | disclosed |