Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GLS | O94925 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610733 | 0.84 | MMP8 (0.54) | KMT2AMMP8SMN1; SMN2ALDH1A1GLS | |
| SCHEMBL15384067 | 0.82 | KMT2A (0.47) | KMT2AMMP8ALDH1A1GLSMEN1 | |
| SCHEMBL2227571 | 0.81 | KMT2A (0.62) | KMT2AMMP8CYP1A2CYP2D6PKM | |
| SCHEMBL12561192 | 0.81 | MMP8 (0.51) | KMT2AMMP8SMN1; SMN2NPSR1GLS | |
| SCHEMBL10608600 | 0.80 | MMP8 (0.57) | KMT2AMMP8CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL3598733 | 0.79 | KMT2A (0.69) | KMT2AMMP8ALDH1A1GLSMEN1 | |
| SCHEMBL27454774 | 0.79 | KMT2A (0.55) | KMT2AMMP8CYP1A2CYP2D6ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27830689 | 0.77 | KMT2A (0.67) | KMT2AMMP8ALDH1A1GLSMEN1 | |
| SCHEMBL2914808 | 0.76 | KMT2A (0.64) | KMT2AMMP8CYP2D6ALDH1A1GLS | |
| SCHEMBL28474562 | 0.75 | MMP8 (0.73) | KMT2AMMP8SMN1; SMN2ALDH1A1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1874989-B | process for preparing -or (R) -4-halo-3-hydroxybutyric acid esters | LONZA AG | 2011-06-29 | — | — | CN | disclosed |
| CN-101883846-A | Reductase polypeptides for the production of azetidinones | CODEXIS INC | 2010-11-10 | — | — | CN | disclosed |
| CN-1874989-A | Process for preparing -or (R) -4-halo-3-hydroxybutyric acid esters | LONZA AG (CH) | 2006-12-06 | — | — | CN | disclosed |