Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 10/20 | 0.59 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030430 | 0.83 | MAPT (0.55) | KCNN4CHRM3CHRM2CHRM1LMNA | |
| Hydrochloric Acid SCHEMBL5252883 | 0.81 | MAPT (0.53) | KCNN4CHRM3CHRM2CHRM1LMNA | |
| SCHEMBL1784375 | 0.75 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL2332073 | 0.75 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL28306699 | 0.74 | KCNN4 (0.50) | KCNN4KCNE1KCNQ1KMT2AKIF11 | |
| SCHEMBL28306690 | 0.74 | KCNN4 (0.50) | KCNN4KCNE1KCNQ1KMT2AKIF11 | |
| SCHEMBL2202827 | 0.74 | CHRM3 (0.47) | CHRM3CHRM2CHRM1LMNACYP2D6 | |
| SCHEMBL5898610 | 0.73 | NOS3 (0.43) | KCNN4LMNAKDM4EKMT2A | |
| SCHEMBL9295790 | 0.73 | CHRM3 (0.59) | CHRM3CHRM2CHRM1LMNACYP2D6 | |
| SCHEMBL22313032 | 0.73 | GRIN1 (0.76) | KCNN4KCNE1KCNQ1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149252-A | Novel substituted tryptamines, phenylalkylamines and the like | INTERNEURON PHARMA (US) | 1997-05-07 | — | — | CN | claimed |
| CN-1149252-A | Novel substituted tryptamines, phenylalkylamines and the like | INTERNEURON PHARMA (US) | 1997-05-07 | — | — | CN | disclosed |