1,4-Dichlorobenzene

1,4-Dichlorobenzene

SCHEMBL27455358

CCC=O.Clc1ccc(Cl)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 3/20 0.53
▸ ALDH1A1 P00352 2/20 0.53
▸ TDP1 Q9NUW8 2/20 0.53
▸ HSD17B10 Q99714 1/20 0.50
▸ LMNA P02545 1/20 0.47
▸ CYP2A6 P11509 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ ELANE P08246 1/20 0.39
▸ IDO1 P14902 2/20 0.38
▸ CYP3A4 P08684 2/20 0.38
▸ CES2 O00748 2/20 0.38
▸ CES1 P23141 2/20 0.38
▸ HTT P42858 1/20 0.38
▸ GSK3B P49841 1/20 0.37
▸ PTGER4 P35408 1/20 0.36
▸ TSHR P16473 2/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ TACR2 P21452 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionaldehyde SCHEMBL28014512 0.88 MAPT (0.44) MAPK1ALDH1A1TDP1HSD17B10LMNA
Chlorobenzene SCHEMBL27453118 0.87 TSHR (0.55) MAPK1ALDH1A1TDP1HSD17B10LMNA
Propionaldehyde SCHEMBL28084160 0.84 POLB (0.52) MAPK1ALDH1A1TDP1HSD17B10LMNA
Propionaldehyde SCHEMBL28868428 0.82 KMT2A (0.55) ALDH1A1LMNASMN1; SMN2CES2CES1
Propionaldehyde SCHEMBL27792856 0.79 CHRM2 (0.44) MAPK1ALDH1A1TDP1TSHRTAAR1
Chlorobenzene SCHEMBL27888130 0.79 TSHR (0.46) MAPK1ALDH1A1TDP1HSD17B10LMNA
1,2-Dichlorobenzene SCHEMBL27361512 0.78 TSHR (0.53) MAPK1ALDH1A1TDP1LMNASMN1; SMN2
1,4-Dichlorobenzene SCHEMBL27808925 0.77 LMNA (0.67) LMNACYP2A6SMN1; SMN2ELANEIDO1
Propionaldehyde SCHEMBL4244592 0.75 ALDH1A1 (0.60) MAPK1ALDH1A1TDP1LMNASMN1; SMN2
SCHEMBL1609713 0.74 HSD17B10 (0.55) HSD17B10LMNACYP2A6PTGER4TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109749013-A A kind of polypropylene printing membrane preparation method of high strength anti-abrasion flower 贵州金田新材料科技有限公司 2019-05-14 — — CN claimed
CN-104151499-A Preparation method of printable polypropylene material UNIV SOUTH CHINA TECH 2014-11-19 — — CN claimed
CN-101226332-B Method for manufacturing barrier wall slurry IRICO GROUP CORP 2011-02-16 — — CN claimed
CN-100552859-C A kind of preparation method of photoelectric sensitivity conductive slurry IRICO GROUP CO LTD (CN) 2009-10-21 — — CN claimed
CN-101226862-A Method for preparation of photoelectric sensitivity conductive slurry IRICO GROUP (CN) 2008-07-23 — — CN claimed
CN-101226332-A Method for manufacturing barrier wall slurry IRICO GROUP (CN) 2008-07-23 — — CN claimed
CN-110204487-A A kind of synthetic method of quinoline 江南大学 2019-09-06 — — CN disclosed
CN-105733476-B Polarization film and image display device with adhesive phase 日东电工株式会社 2019-06-28 — — CN disclosed
CN-104830243-B Double-sided adhesive sheet and its manufacturing method 日东电工株式会社 2019-06-14 — — CN disclosed
CN-109749013-A A kind of polypropylene printing membrane preparation method of high strength anti-abrasion flower 贵州金田新材料科技有限公司 2019-05-14 — — CN disclosed
CN-108887265-A Promote the regulator of plant failure cell fast-growth 金华市景和科技有限公司 2018-11-27 — — CN disclosed
CN-103492516-B Adhesive, adhesive phase and bonding sheet 日东电工株式会社 2018-04-27 — — CN disclosed
CN-107880586-A Colorant, colored resin composition comprising the same, and color filter 乐金显示有限公司 2018-04-06 — — CN disclosed
CN-1717763-A Unbaked laminate for producing front plate of plasma display device, and method for producing front plate of plasma display device TOKYO OHKA KOGYO CO LTD (JP) 2006-01-04 — — CN disclosed
CN-1680273-A Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 2005-10-12 — — CN disclosed
CN-1526696-A Process for producing N- [ 1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide 住友化学工业株式会社 2004-09-08 — — CN disclosed
CN-1524845-A Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide 住友化学工业株式会社 2004-09-01 — — CN disclosed
CN-1514848-A Curable unsaturated resin composition 大日本油墨化学工业株式会社 2004-07-21 — — CN disclosed
CN-1153762-C Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide 住友化学工业株式会社 2004-06-16 — — CN disclosed
CN-1131146-A Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 1996-09-18 — — CN disclosed
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