Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionaldehyde SCHEMBL27524950 | 0.88 | TDP1 (0.53) | MAPTALDH1A1MAPK1TDP1POLB | |
| 1,4-Dichlorobenzene SCHEMBL27455358 | 0.88 | MAPK1 (0.53) | ALDH1A1MAPK1TDP1HSD17B10HTT | |
| Propane SCHEMBL28210232 | 0.83 | LMNA (0.47) | MAPTTHRBDRD2DRD4DRD3 | |
| Propionaldehyde SCHEMBL27520963 | 0.77 | ALDH1A1 (0.41) | MAPTALDH1A1MAPK1TDP1NPC1 | |
| SCHEMBL7024646 | 0.77 | — | — | |
| SCHEMBL5776485 | 0.77 | — | — | |
| SCHEMBL35226 | 0.77 | — | — | |
| Fluorobenzene SCHEMBL27296706 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MAPK1TDP1HSD17B10TP53 | |
| Chlorobenzene SCHEMBL27453118 | 0.76 | TSHR (0.55) | MAPTALDH1A1MAPK1TDP1HSD17B10 | |
| Formic Acid SCHEMBL27921691 | 0.76 | ALDH1A1 (0.47) | MAPTTHRBDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109320504-A | A kind of preparation method of epoxiconazole | 湖南湘硕化工有限公司 | 2019-02-12 | — | — | CN | claimed |
| CN-109734581-A | A kind of preparation method of the chloro- 5- fluorobenzoyl chloride of fluoroquinolones intermediate 2,4- bis- | 和鼎（南京）医药技术有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-109320504-A | A kind of preparation method of epoxiconazole | 湖南湘硕化工有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-109320504-A | A kind of preparation method of epoxiconazole | 湖南湘硕化工有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-107118096-A | A kind of preparation method of the fluorobenzoyl chloride of 2,4 dichloro 5 | 和鼎（南京）医药技术有限公司 | 2017-09-01 | — | — | CN | disclosed |
| CN-104610034-B | The preparation method of the chloro-5-fluoro acetophenone of a kind of 2,4-bis- | ZHEJIANG YONGTAI TECHNOLOGY CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-104610034-A | Preparation method of 2,4-dichloro-5-fluoroacetophenone | ZHEJIANG YONGTAI TECHNOLOGY CO LTD | 2015-05-13 | — | — | CN | disclosed |