Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950581 | 0.75 | CES2 (0.48) | CTSLL3MBTL1CES2CES1HDAC1 | |
| SCHEMBL9353591 | 0.75 | CES2 (0.59) | CTSLL3MBTL1CES2CES1HDAC1 | |
| SCHEMBL906035 | 0.74 | CES2 (0.57) | L3MBTL1CES2CES1HDAC1HDAC6 | |
| SCHEMBL12942306 | 0.74 | CES2 (0.47) | CTSLCES2CES1HDAC1HDAC6 | |
| SCHEMBL28530493 | 0.73 | CTSL (0.50) | CTSLCES2CES1HDAC1HDAC6 | |
| Fluoride SCHEMBL25408744 | 0.73 | MAOB (0.50) | CTSLCES2CES1HDAC1HDAC6 | |
| Fluoride SCHEMBL31239659 | 0.73 | MAOB (0.50) | CTSLCES2CES1HDAC1HDAC6 | |
| SCHEMBL8704652 | 0.72 | CES2 (0.55) | CTSLL3MBTL1CES2CES1HDAC1 | |
| SCHEMBL23368196 | 0.72 | L3MBTL1 (0.49) | L3MBTL1PARP1C1SALDH1A1KDM4E | |
| SCHEMBL3456365 | 0.72 | L3MBTL1 (0.57) | L3MBTL1PARP1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1108289-C | Difluoroprostaglundin derivatives and their use | ASAHI GLASS CO LTD (JP) | 2003-05-14 | — | — | CN | disclosed |
| CN-1187486-A | Difluoroprostaglundin Derivatives and their use | ASAHI GLASS CO LTD (JP) | 1998-07-15 | — | — | CN | disclosed |