Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 5/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27801700 | 0.84 | TNKS2 (0.49) | SMN1; SMN2TSHRMAPTGAAKMT2A | |
| SCHEMBL27406608 | 0.77 | IDO1 (0.38) | SMN1; SMN2MAPTGAAKMT2AMEN1 | |
| SCHEMBL19072682 | 0.76 | CREBBP (0.42) | CREBBPBRPF1SMN1; SMN2MAPTGAA | |
| SCHEMBL27558447 | 0.71 | TSHR (0.33) | TSHR | |
| SCHEMBL1556866 | 0.67 | IDO1 (0.48) | CREBBPSMN1; SMN2TSHRMAPTGAA | |
| SCHEMBL4215459 | 0.67 | GAA (0.51) | CREBBPMAPTGAABRD4 | |
| SCHEMBL27404564 | 0.67 | MAPT (0.42) | CREBBPBRPF1SMN1; SMN2TSHRMAPT | |
| SCHEMBL13949315 | 0.66 | MAPT (0.43) | CREBBPBRPF1SMN1; SMN2TSHRMAPT | |
| SCHEMBL28278551 | 0.66 | MAPT (0.43) | CREBBPBRPF1SMN1; SMN2TSHRMAPT | |
| SCHEMBL3044369 | 0.65 | MAPT (0.50) | CREBBPBRPF1SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1126837-A | Detection of high risk factor to develop cataract and a reagent kit for the detection | SENJU PHARMA CO (JP) | 1996-07-17 | — | — | CN | disclosed |