Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FER | P16591 | 1/20 | 0.42 |
| ▸ | LTK | P29376 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27458092 | 0.84 | CREBBP (0.38) | TNKS2KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL8507044 | 0.81 | TNKS2 (0.49) | TNKS2KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL27558447 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL28754030 | 0.76 | TGM2 (0.49) | KMT2AMEN1MAPK1CYP1A2LRRK2 | |
| SCHEMBL19465426 | 0.72 | TNKS2 (0.55) | TNKS2KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL27599803 | 0.70 | CES1 (0.34) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL1708833 | 0.70 | TNKS2 (0.57) | TNKS2KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL8143860 | 0.69 | TNKS2 (0.56) | TNKS2KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL1075473 | 0.68 | TNKS2 (0.55) | TNKS2KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL20510203 | 0.68 | TNKS2 (0.55) | TNKS2KMT2AGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679314-A | The double inhibition compound of enzyme PDE7 and/or PDE4, medical composition and its use | CONSEJO SUPERIOR INVESTIGACION | 2010-03-24 | — | — | CN | disclosed |