SCHEMBL27458277

SCHEMBL27458277

O=C(O)CCc1ccccc1Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.63
FFAR1 O14842 5/20 0.59
HTR2A P28223 1/20 0.57
HDAC3 O15379 1/20 0.53
MAPK1 P28482 1/20 0.53
ADRA1A P35348 1/20 0.53
HDAC4 P56524 1/20 0.53
SLC6A3 Q01959 1/20 0.53
HDAC1 Q13547 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC10 Q969S8 1/20 0.53
HDAC11 Q96DB2 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
HDAC9 Q9UKV0 1/20 0.53
HDAC5 Q9UQL6 1/20 0.53
PTGER1 P34995 4/20 0.52
PTGER4 P35408 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9173189 0.88 FFAR1 (0.53) KEAP1FFAR1HTR2APTGER1PTGER4
SCHEMBL11633504 0.88 FFAR1 (0.51) KEAP1FFAR1HTR2APLA2G4AFFAR4
SCHEMBL59198 0.87 KEAP1 (0.65) KEAP1FFAR1HDAC3MAPK1ADRA1A
SCHEMBL6505817 0.85 HTR2A (0.58) KEAP1FFAR1HTR2AHDAC3MAPK1
SCHEMBL9785808 0.84 FFAR1 (0.55) KEAP1FFAR1HDAC3MAPK1ADRA1A
SCHEMBL9566135 0.82 CYP4F2 (0.53) KEAP1FFAR1HDAC3MAPK1ADRA1A
SCHEMBL9179978 0.82 CA1 (0.46) KEAP1FFAR1PTGER1PTGER4PTGER3
SCHEMBL17940787 0.82 HTR2A (0.50) KEAP1FFAR1HTR2AHDAC3MAPK1
SCHEMBL19140662 0.82 FOLH1 (0.60) KEAP1FFAR1HDAC3MAPK1ADRA1A
SCHEMBL9487508 0.81 MAPT (0.72) KEAP1FFAR1HDAC3MAPK1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107602406-B Preparation method and content control method in racecadotril as two kinds of impurity of external standard 陕西汉江药业集团股份有限公司 2019-08-20 CN disclosed
CN-106833773-B M20 methanol gasoline modified alcohol additives 甘肃桑田清洁能源开发有限公司 2018-05-18 CN disclosed
CN-107602406-A In racecadotril as external standard two kinds of impurity preparation method and content control method 陕西汉江药业集团股份有限公司 2018-01-19 CN disclosed
CN-106833773-A M20 methanol gasoline modified alcohol additives 甘肃桑田清洁能源开发有限公司 2017-06-13 CN disclosed
CN-102791674-B Compound having trimethylene structure, polymer compound containing unit that has trimethylene structure, and reactive compound having trimethylene structure 日立化成株式会社 2017-05-17 CN disclosed
CN-1126438-A Method of combating acyclovir-resistant herpes simplex viral infections BIO MEGA BOEHRINGER INGELHEIM (CA) 1996-07-10 CN disclosed