Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2951034 | 1.00 | MAPT (0.46) | MAPTTP53KMT2AALDH1A1MEN1 | |
| SCHEMBL5940974 | 0.98 | MAPT (0.47) | MAPTTP53KMT2AALDH1A1MEN1 | |
| Bromide SCHEMBL2954116 | 0.86 | ALDH1A1 (0.48) | MAPTTP53KMT2AALDH1A1MEN1 | |
| Bromide SCHEMBL27893556 | 0.86 | ALDH1A1 (0.48) | MAPTTP53KMT2AALDH1A1MEN1 | |
| Bromide SCHEMBL2954210 | 0.85 | MAPT (0.42) | MAPTTP53KMT2AALDH1A1MEN1 | |
| Bromide SCHEMBL27876873 | 0.85 | MAPT (0.42) | MAPTTP53KMT2AALDH1A1MEN1 | |
| SCHEMBL9841898 | 0.85 | MAPT (0.44) | MAPTTP53KMT2AALDH1A1MEN1 | |
| Bromide SCHEMBL31588381 | 0.84 | KMT2A (0.54) | MAPTTP53KMT2AALDH1A1MEN1 | |
| SCHEMBL6939772 | 0.84 | ALDH1A1 (0.46) | MAPTTP53KMT2AALDH1A1MEN1 | |
| Bromide SCHEMBL7401678 | 0.84 | KMT2A (0.54) | MAPTTP53KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104047036-B | Copper plating solution and production and preparation method thereof | 麦德美乐思美国有限公司 | 2018-11-02 | — | — | CN | claimed |
| CN-104047036-A | Copper plating solutions and method of making and using such solutions | OMG ELECTRONIC CHEMICALS LLC | 2014-09-17 | — | — | CN | claimed |
| CN-104047036-B | Copper plating solution and production and preparation method thereof | 麦德美乐思美国有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-104047036-A | Copper plating solutions and method of making and using such solutions | OMG ELECTRONIC CHEMICALS LLC | 2014-09-17 | — | — | CN | disclosed |
| CN-1142778-C | Use of thiazolium compounds for preventing and reversing the formation of advanced glycosylation endproducts | ¶ | 2004-03-24 | — | — | CN | disclosed |
| CN-1185736-A | Use of thiazolium compounds for preventing and preverting the formation of advanced glycosylation endproducts | ALTEON INC (US) | 1998-06-24 | — | — | CN | disclosed |