SCHEMBL9841898

SCHEMBL9841898

[O]C(=O)CN1CSc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.44
TP53 P04637 3/20 0.44
NOTUM Q6P988 1/20 0.41
ALDH1A1 P00352 6/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC6 Q9UBN7 2/20 0.41
MITF O75030 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
GFER P55789 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
THRB P10828 1/20 0.39
HSD17B3 P37058 1/20 0.39
USP2 O75604 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5940974 0.86 MAPT (0.47) MAPTTP53NOTUMALDH1A1KMT2A
SCHEMBL6935721 0.85 MAPT (0.43) MAPTTP53NOTUMALDH1A1KMT2A
Bromide SCHEMBL27458290 0.85 MAPT (0.46) MAPTTP53NOTUMALDH1A1KMT2A
Bromide SCHEMBL2951034 0.85 MAPT (0.46) MAPTTP53NOTUMALDH1A1KMT2A
Bromide SCHEMBL27876873 0.83 MAPT (0.42) MAPTTP53NOTUMALDH1A1KMT2A
Hydrochloric Acid SCHEMBL27306778 0.83 MAPT (0.42) MAPTTP53NOTUMALDH1A1KMT2A
Bromide SCHEMBL2954210 0.83 MAPT (0.42) MAPTTP53NOTUMALDH1A1KMT2A
SCHEMBL6939772 0.82 ALDH1A1 (0.46) MAPTTP53ALDH1A1KMT2AKDM4E
SCHEMBL11193182 0.82 MAPT (0.41) MAPTTP53NOTUMALDH1A1KMT2A
SCHEMBL6937974 0.81 LMNA (0.50) MAPTTP53NOTUMALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0452811-A2 Package of photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-10-23 EP disclosed
US-4237214-A P-DIHYDROXYBENZENE DEVELOPING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1980-12-02 US disclosed