⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235190 | 0.75 | — | — | |
| SCHEMBL216358 | 0.74 | — | — | |
| SCHEMBL15031 | 0.74 | CALM1 (0.32) | — | |
| SCHEMBL14354468 | 0.71 | — | — | |
| SCHEMBL134463 | 0.70 | — | — | |
| SCHEMBL190816 | 0.70 | — | — | |
| SCHEMBL41215 | 0.70 | — | — | |
| SCHEMBL24915 | 0.70 | — | — | |
| SCHEMBL65919 | 0.70 | — | — | |
| SCHEMBL1480704 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602809-A | Inhibitors of isoxazolidine derived receptor interacting protein kinase 1(RIPK 1) | 戴纳立制药公司 | 2018-09-28 | — | — | CN | claimed |
| CN-108383828-A | 1 new, 2- as chemokine receptor modulators is bis--sulfamide derivative | 阿勒根公司 | 2018-08-10 | — | — | CN | claimed |
| CN-106660994-A | Phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-05-10 | — | — | CN | claimed |
| CN-103608350-B | Triazolopyridine compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-25 | — | — | CN | claimed |
| CN-103068797-B | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2015-03-11 | — | — | CN | claimed |
| CN-103384662-A | Novel 1, 2-bis-sulfonamide derivatives as chemokine receptor modulators | ALLERGAN INC | 2013-11-06 | — | — | CN | claimed |
| CN-102149689-A | Substituted 1-benzyl-cinnolin-4 (1H) -one derivatives, preparation thereof and therapeutic use thereof | SANOFI AVENTIS | 2011-08-10 | — | — | CN | claimed |
| CN-101035770-B | 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA NV | 2011-02-23 | — | — | CN | claimed |
| CN-100441185-C | 8- (3-biaryl) phenylquinoline phosphodiesterase-4 inhibitors | MERCK FROSST CANADA INC (CA) | 2008-12-10 | — | — | CN | claimed |
| CN-100369899-C | Substituted indazoles with anti-cancer activity | AVENTIS PHARMA SA (FR) | 2008-02-20 | — | — | CN | claimed |
| CN-1910157-A | N' - (1, 5-diphenyl-1H-pyrazol-3-yl) sulfonamide derivatives having affinity for the CBI receptor | SANOFI AVENTIS (FR) | 2007-02-07 | — | — | CN | claimed |
| CN-1860114-A | Benzoxazinone-derived sulfonamide compounds, process for their preparation and their use as pharmaceuticals | ESTEVE LABOR DR (ES) | 2006-11-08 | — | — | CN | claimed |
| CN-1812787-A | 8- (3-biaryl) phenylquinoline phosphodiesterase-4 inhibitors | MERCK FROSST CANADA INC (CA) | 2006-08-02 | — | — | CN | claimed |
| CN-1213040-C | Serine protease inhibitors | LILLY CO ELI (US) | 2005-08-03 | — | — | CN | claimed |
| CN-1642922-A | Substituted indazoles with anti-cancer activity | AVENTIS PHARMA SA (FR) | 2005-07-20 | — | — | CN | claimed |
| CN-1639147-A | Synthesis of 4, 5-dihydro-pyrazolo [3, 4-c ] pyridin-2-ones | BRISTOL MYERS SQUIBB CO (US) | 2005-07-13 | — | — | CN | claimed |
| CN-1481358-A | Amide derivatives and their use in the treatment of thromboembolic disorders and tumours | Ĭ��ר���ɷ�����˾ | 2004-03-10 | — | — | CN | claimed |
| CN-1444481-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 2003-09-24 | — | — | CN | claimed |
| CN-1439008-A | 1-(heteroaryl-henyl)-condensed pyrazol derivatives as factor XA inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2003-08-27 | — | — | CN | claimed |
| CN-1151157-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARM (GB) | 1997-06-04 | — | — | CN | claimed |