⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310013 | 0.80 | — | — | |
| SCHEMBL8713096 | 0.78 | TSHR (0.40) | — | |
| SCHEMBL216358 | 0.78 | — | — | |
| SCHEMBL15031 | 0.78 | CALM1 (0.32) | — | |
| SCHEMBL3151244 | 0.77 | LTA4H (0.38) | — | |
| SCHEMBL79754 | 0.75 | CALM1 (0.50) | — | |
| SCHEMBL6425240 | 0.75 | TDP1 (0.48) | — | |
| SCHEMBL158757 | 0.75 | TDP1 (0.33) | — | |
| SCHEMBL65919 | 0.74 | — | — | |
| SCHEMBL134463 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3878 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | claimed |
| US-20240174643-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-05-30 | — | — | US | claimed |
| WO-2024101411-A1 | CURABLE COMPOSITION FOR ORGANIC EL ELEMENTS, CURED PRODUCT FOR ORGANIC EL ELEMENTS AND METHOD FOR PRODUCING SAME, ORGANIC EL ELEMENT, AND POLYMER | JSR株式会社 | 2024-05-16 | — | — | WO | claimed |
| CN-118005569-A | 6-Aminoquinoxaline compound and preparation method and application thereof | 华南理工大学 | 2024-05-10 | — | — | CN | claimed |
| EP-4355741-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2024-04-24 | — | — | EP | claimed |
| CN-117813084-A | Bruise and filler compositions and methods of use | 阿拉斯廷护肤品股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| WO-2024052701-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | claimed |
| WO-2024033389-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | claimed |
| EP-4301752-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Cambridge Enterprise Limited (GB) | 2024-01-10 | — | — | EP | claimed |
| WO-2024003259-A1 | TEAD INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-04 | — | — | WO | claimed |
| EP-0080975-B1 | PHOTOSENSITIVE POLYMERS | CIBA-GEIGY AG (CH) | 1986-02-26 | — | — | EP | claimed |
| US-4560643-A | BLEND OF AROMATIC KETONE, POLYMER, AND GROUP IB OR EIGHT METAL SALT | CIBA GEIGY CORPORATION (US) | 1985-12-24 | — | — | US | claimed |
| EP-0110833-A1 | Use of light-sensitive product mixtures for electroless metal deposition | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | claimed |
| US-4443436-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1984-04-17 | — | — | US | claimed |
| EP-0027948-B1 | TETRAHYDRO-FLUORENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | MERCK & CO. INC. (US) | 1984-03-21 | — | — | EP | claimed |
| EP-0080975-A1 | Photosensitive polymers | CIBA-GEIGY AG (CH) | 1983-06-08 | — | — | EP | claimed |
| US-4317922-A | [(5,6,9a-Substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alkanoic and cycloalkanoic acids and their analogs, esters, salts and derivatives | MERCK & CO., INC. (US) | 1982-03-02 | — | — | US | claimed |
| US-4316043-A | ANTIEDEMIC AGENTS | MERCK & CO., INC. (US) | 1982-02-16 | — | — | US | claimed |
| US-4276295-A | VASODILATORS, HYPOTENSIVE, ANTIATHEROSCLEROTIC | Ishikawa, Masayuki (JP) | 1981-06-30 | — | — | US | claimed |
| EP-0027948-A1 | Tetrahydro-fluorene compounds, processes for their preparation and pharmaceutical compositions thereof | MERCK & CO. INC. (US) | 1981-05-06 | — | — | EP | claimed |