Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | WRN | Q14191 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068963 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPTTHRBCYP3A4TSHR | |
| SCHEMBL28130248 | 0.78 | PTGS1 (0.50) | ALDH1A1MAPTCYP1A2BLMHPGD | |
| SCHEMBL27459207 | 0.78 | PTGS1 (0.50) | ALDH1A1MAPTCYP1A2BLMHPGD | |
| SCHEMBL28287170 | 0.77 | ALDH1A1 (0.35) | ALDH1A1CYP3A4TSHRATMTDP1 | |
| SCHEMBL27906685 | 0.77 | ALDH1A1 (0.35) | ALDH1A1CYP3A4TSHRATMTDP1 | |
| SCHEMBL12021046 | 0.74 | PTGS1 (0.57) | ALDH1A1MAPTTHRBCNR1CYP1A2 | |
| SCHEMBL12021170 | 0.73 | MGLL (0.44) | ALDH1A1MAPTTHRBCNR1CYP1A2 | |
| SCHEMBL28075242 | 0.73 | ALDH1A1 (0.33) | ALDH1A1CYP3A4TSHRATMTDP1 | |
| SCHEMBL357100 | 0.73 | MGLL (0.48) | ALDH1A1MAPTTHRBCYP3A4TSHR | |
| SCHEMBL15978267 | 0.72 | CYP3A4 (0.52) | ALDH1A1MAPTCYP3A4TSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105813656-A | LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA | 夏尔人类遗传性治疗公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105813721-A | Device for dispensing particles in small volumes | 不列颠哥伦比亚大学 | 2016-07-27 | — | — | CN | disclosed |