Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutyramide SCHEMBL6027666 | 0.95 | LMNA (0.50) | LMNAALDH1A1TDP1CA1CA2 | |
| Isobutyramide SCHEMBL7705026 | 0.82 | TDP1 (0.53) | LMNAALDH1A1TDP1CA1CA2 | |
| Glycerin SCHEMBL8537586 | 0.81 | LMNA (0.53) | LMNAALDH1A1TDP1KDM4EDUSP3 | |
| Isobutyramide SCHEMBL9687358 | 0.81 | — | — | |
| Glycerin SCHEMBL6841403 | 0.79 | LMNA (0.50) | LMNAALDH1A1KDM4EDUSP3MEN1 | |
| Glycerin SCHEMBL19182834 | 0.78 | LMNA (0.56) | LMNAALDH1A1TDP1KDM4EDUSP3 | |
| Isobutyramide SCHEMBL10569453 | 0.78 | TSHR (0.38) | LMNAALDH1A1CA1CA2CA12 | |
| Glycerin SCHEMBL4538901 | 0.78 | LMNA (0.64) | LMNAALDH1A1TDP1THRBOR51E2 | |
| Glycerin SCHEMBL8328163 | 0.78 | LMNA (0.64) | LMNAALDH1A1TDP1THRBOR51E2 | |
| Glycerin SCHEMBL4733394 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147472-C | Benzamide formulation with histone deacetylase inhibitor activity | ���鹫˾ | 2004-04-28 | — | — | CN | disclosed |
| CN-1371366-A | Benzamide formulations with histone deacetylase inhibitor activity | SCHERING AG (DE) | 2002-09-25 | — | — | CN | disclosed |