Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TKT | P29401 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619744 | 0.77 | CCR9 (0.40) | PPARGPPARANPC1POLBRAB9A | |
| SCHEMBL17403389 | 0.76 | CA12 (0.33) | PTGS2PPARGPPARANPC1POLB | |
| SCHEMBL1743280 | 0.74 | TKT (0.39) | PPARGPPARANPC1POLBRAB9A | |
| SCHEMBL24501299 | 0.70 | PPARG (0.31) | PPARGPPARANPC1POLBRAB9A | |
| SCHEMBL29695036 | 0.70 | PPARG (0.31) | PPARGPPARANPC1POLBRAB9A | |
| SCHEMBL38655572 | 0.70 | CYP2C19 (0.46) | PPARGPPARANPC1POLBRAB9A | |
| SCHEMBL29525326 | 0.70 | TRPV4 (0.52) | TKT | |
| SCHEMBL132198 | 0.70 | TRPV4 (0.52) | TKT | |
| SCHEMBL17583134 | 0.67 | KCNQ3 (0.42) | NPC1POLBTKT | |
| SCHEMBL2938892 | 0.66 | PPARG (0.39) | PPARGPPARANPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127252-A | Branched-amino-sbustituted thiazoles, processes for their preparation and the pharmaceutical compositions which contain them | SANOFI SA (FR) | 1996-07-24 | — | — | CN | disclosed |