Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12303328 | 0.85 | KDM4E (0.41) | CA2PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL619744 | 0.82 | CCR9 (0.40) | CA12CA1CA2CA4CA6 | |
| SCHEMBL1743280 | 0.79 | TKT (0.39) | CA12CA1CA2CA4CA6 | |
| SCHEMBL19413034 | 0.77 | ESR1 (0.39) | LMNA | |
| SCHEMBL27460229 | 0.76 | PTGS2 (0.32) | CA12CA1CA2CA4CA6 | |
| SCHEMBL217684 | 0.75 | CCR1 (0.43) | RAB9AKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL17433153 | 0.75 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2MAPTATM | |
| SCHEMBL17403395 | 0.75 | TRPV4 (0.52) | — | |
| SCHEMBL29525326 | 0.75 | TRPV4 (0.52) | TKTCYP3A4 | |
| SCHEMBL132198 | 0.75 | TRPV4 (0.52) | TKTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9324604-B2 | Gap-fill methods | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2016-04-26 | — | — | US | disclosed |
| US-20160005641-A1 | GAP-FILL METHODS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2016-01-07 | — | — | US | disclosed |