Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729117 | 0.86 | HDAC8 (0.47) | ACACBHDAC8PTPN1ATMITGB3 | |
| SCHEMBL27460864 | 0.82 | PTPN1 (0.47) | PTPN1CTSK | |
| SCHEMBL8729115 | 0.82 | ADRB3 (0.49) | ACACBHDAC8PTPN1ATMITGB3 | |
| SCHEMBL8729106 | 0.82 | ADRB3 (0.49) | ACACBHDAC8PTPN1ATMITGB3 | |
| SCHEMBL8732286 | 0.79 | ACACB (0.49) | ACACBHDAC8PTPN1ITGB3ITGA2B | |
| SCHEMBL8729003 | 0.79 | ACACB (0.49) | ACACBHDAC8PTPN1ITGB3ITGA2B | |
| SCHEMBL8729119 | 0.79 | ACACB (0.49) | ACACBHDAC8PTPN1ITGB3ITGA2B | |
| SCHEMBL27477595 | 0.78 | TAAR1 (0.44) | — | |
| SCHEMBL14884502 | 0.77 | ACACB (0.47) | ACACBHDAC8ITGB3ITGA2B | |
| SCHEMBL3676162 | 0.77 | NPC1 (0.63) | ATMCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1159797-A | Aryloxy and arylthiopropanolamine derivative suseful as beta 3-adrenoreceptor agonists and antagonists of the beta 1 and beta 2-adrenoreceptors and pharmaceutical composition thereof | SMITHKLINE BEECHAM PLC (GB) | 1997-09-17 | — | — | CN | disclosed |