Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8230392 | 0.83 | GLA (0.47) | PTPN1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL27460415 | 0.82 | ACACB (0.45) | PTPN1CTSK | |
| SCHEMBL27460037 | 0.80 | PTPN1 (0.47) | PTPN1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14812122 | 0.80 | CA2 (0.48) | MAPTNAMPTCTSKKMT2AGLA | |
| SCHEMBL8728998 | 0.78 | CA2 (0.48) | PTPN1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL27741033 | 0.77 | ACACB (0.59) | NPC1RAB9AMAPTSMN1; SMN2NAMPT | |
| SCHEMBL27479632 | 0.77 | AOX1 (0.42) | SMN1; SMN2TAAR1LTA4HEPHX2 | |
| SCHEMBL13886599 | 0.76 | EPHX2 (0.59) | PTPN1NPC1RAB9ANAMPTCTSK | |
| SCHEMBL5142116 | 0.76 | GLA (0.49) | NPC1RAB9AMAPTSMN1; SMN2NAMPT | |
| SCHEMBL14763270 | 0.76 | CA1 (0.49) | NPC1RAB9AMAPTSMN1; SMN2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1159797-A | Aryloxy and arylthiopropanolamine derivative suseful as beta 3-adrenoreceptor agonists and antagonists of the beta 1 and beta 2-adrenoreceptors and pharmaceutical composition thereof | SMITHKLINE BEECHAM PLC (GB) | 1997-09-17 | — | — | CN | disclosed |