Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | KAT6A | Q92794 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14679321 | 0.86 | HTT (0.66) | HTTSMN1; SMN2BCAT1GAAKAT6A | |
| SCHEMBL4584839 | 0.83 | PPARA (0.55) | HTTSMN1; SMN2BCAT1MEN1KMT2A | |
| SCHEMBL5537015 | 0.81 | HTT (0.59) | HTTSMN1; SMN2BCAT1GAAKAT6A | |
| SCHEMBL9733160 | 0.77 | BCAT1 (1.00) | HTTSMN1; SMN2BCAT1GAAKAT6A | |
| SCHEMBL2361900 | 0.77 | BCAT1 (0.67) | HTTSMN1; SMN2BCAT1GAAKAT6A | |
| SCHEMBL11532705 | 0.76 | BCAT1 (0.71) | HTTSMN1; SMN2BCAT1GAAKAT6A | |
| SCHEMBL2746048 | 0.75 | BCAT1 (0.65) | HTTSMN1; SMN2BCAT1GAAKAT6A | |
| Urea SCHEMBL28099509 | 0.75 | BCAT1 (0.65) | HTTSMN1; SMN2BCAT1GAAKAT6A | |
| SCHEMBL11513730 | 0.74 | MEN1 (0.72) | HTTSMN1; SMN2BCAT1GAAKAT6A | |
| SCHEMBL7627545 | 0.74 | BCAT1 (0.62) | HTTSMN1; SMN2BCAT1GAAKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20120208813-A1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVES | SHIONOGI & CO., LTD. | 2012-08-16 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20080103139-A1 | 3-Carbamoyl-2-Pyridone Derivative | SHIONOGI & CO. LTD. (JP) | 2008-05-01 | — | — | US | disclosed |
| EP-1806342-A1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2007-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208813-A1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVES | CNR2, CNR1, HRH4 | HTT 4417/4885SMN1; SMN2 4550/4885BCAT1 3948/4885 |
| US-20080103139-A1 | 3-Carbamoyl-2-Pyridone Derivative | CNR1, CNR2, HRH4 | HTT 4351/4885SMN1; SMN2 4482/4885BCAT1 3241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.