Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489636 | 0.84 | PTGS2 (0.48) | PTGS2RAPGEF4LMNATAS2R14 | |
| SCHEMBL6036637 | 0.73 | PTGS2 (0.53) | PTGS2HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20332068 | 0.70 | MAPT (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL800329 | 0.70 | LMNA (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6036720 | 0.70 | PTGS2 (0.46) | PTGS2HPGDMAPK10CYP1A2CYP3A4 | |
| SCHEMBL16723454 | 0.69 | ALDH1A1 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27439987 | 0.67 | PTGS2 (0.51) | PTGS2HPGDLMNAMEN1KMT2A | |
| SCHEMBL28534333 | 0.67 | PDK2 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26746830 | 0.67 | NPC1 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27489637 | 0.67 | PTGS2 (0.53) | PTGS2RAPGEF4HPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1140500-C | Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives | ��˹��ŵ�� | 2004-03-03 | — | — | CN | disclosed |
| CN-1268112-A | Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives thereof | NOVARTIS AG (CH) | 2000-09-27 | — | — | CN | disclosed |