Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679372 | 0.86 | MT-CO2 (0.46) | MT-CO2UCHL1AKR1C3AKR1C2TDP1 | |
| SCHEMBL1679568 | 0.82 | AKR1C3 (0.44) | AKR1C3AKR1C2 | |
| SCHEMBL20752378 | 0.80 | AAK1 (0.40) | USP30AAK1PRMT5WDR77UCHL1 | |
| SCHEMBL28817169 | 0.80 | AAK1 (0.42) | USP30AAK1PRMT5WDR77 | |
| SCHEMBL4161409 | 0.77 | GABRA1 (0.38) | USP30AAK1BACE1BACE2PRMT5 | |
| SCHEMBL2128253 | 0.75 | MT-CO2 (0.40) | APPAAK1MT-CO2UCHL1TDP1 | |
| SCHEMBL28817172 | 0.75 | CYP1A2 (0.34) | USP30UCHL1 | |
| SCHEMBL27463423 | 0.74 | APP (0.50) | APPMT-CO2AKR1C3AKR1C2TDP1 | |
| SCHEMBL15031655 | 0.74 | LPL (0.34) | AAK1 | |
| SCHEMBL12072363 | 0.74 | CA12 (0.49) | AAK1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622970-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112854-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024112854-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |