Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.52 |
| ▸ | NOS2 | P35228 | 4/20 | 0.52 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17595010 | 0.79 | RECQL (0.35) | NOS3NOS2KDM4CSIGMAR1WDR5 | |
| SCHEMBL31283794 | 0.79 | RECQL (0.35) | NOS3NOS2KDM4CSIGMAR1WDR5 | |
| SCHEMBL20264735 | 0.75 | HDAC6 (0.40) | KDM4C | |
| SCHEMBL31026257 | 0.73 | NOS3 (0.36) | NOS3NOS2KDM4EKDM4CGABRP | |
| SCHEMBL28165728 | 0.72 | KDM4C (0.38) | KDM4EKDM4CSIGMAR1 | |
| SCHEMBL24028220 | 0.70 | TSHR (0.44) | KDM4EMEN1KMT2ACA2SIGMAR1 | |
| SCHEMBL30212897 | 0.70 | TSHR (0.44) | KDM4EMEN1KMT2ACA2SIGMAR1 | |
| SCHEMBL28168097 | 0.70 | SIGMAR1 (0.42) | SIGMAR1WDR5 | |
| SCHEMBL59927 | 0.69 | NOS3 (1.00) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL29432593 | 0.69 | NOS3 (1.00) | NOS3NOS2NOS1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112854-A1 | INHIBITORS OF RIPK2 AND MEDICAL USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |