Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | SORD | Q00796 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673839 | 0.81 | HTR7 (0.51) | HTR7 | |
| SCHEMBL8326245 | 0.80 | SYK (0.48) | CCNE1CDK2CHI3L1SYK | |
| SCHEMBL8326248 | 0.80 | SYK (0.48) | CCNE1CDK2CHI3L1SYK | |
| SCHEMBL7364016 | 0.77 | MEN1 (0.40) | ALDH1A1NPY5R | |
| SCHEMBL28140950 | 0.75 | FFAR1 (0.44) | NPY5R | |
| SCHEMBL28811056 | 0.75 | CHI3L1 (0.46) | ALDH1A1KDM4EHSD17B10CHI3L1 | |
| SCHEMBL28811057 | 0.75 | CHI3L1 (0.46) | ALDH1A1KDM4EHSD17B10CHI3L1 | |
| SCHEMBL10637154 | 0.74 | HRH3 (0.45) | CCNE1CDK2CDK5CHI3L1 | |
| SCHEMBL6963258 | 0.72 | MEN1 (0.40) | ALDH1A1NPY5R | |
| SCHEMBL3646618 | 0.71 | CHI3L1 (0.41) | ALDH1A1KDM4EHSD17B10HTR7CHI3L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1120334-A | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LTD (GB) | 1996-04-10 | — | — | CN | disclosed |