Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902232 | 0.81 | KIF11 (0.40) | RGS12KIF11ESR1SMN1; SMN2NR1H2 | |
| SCHEMBL30522131 | 0.81 | ESR1 (0.39) | CHRM3KIF11ESR1MEN1KMT2A | |
| Alcohol SCHEMBL29044332 | 0.79 | ESR1 (0.37) | CHRM3KIF11ESR1SMN1; SMN2MEN1 | |
| SCHEMBL246639 | 0.78 | SMN1; SMN2 (0.52) | CHRM3SMN1; SMN2SIGMAR1CHRM2CHRM1 | |
| SCHEMBL28539349 | 0.76 | CHRM2 (0.50) | CHRM3SMN1; SMN2SIGMAR1CHRM2CHRM1 | |
| SCHEMBL936317 | 0.76 | SMN1; SMN2 (0.50) | CHRM3ESR1SMN1; SMN2SIGMAR1CHRM2 | |
| SCHEMBL3906605 | 0.76 | RGS12 (0.44) | CHRM3RGS12KIF11ESR1SMN1; SMN2 | |
| SCHEMBL3389968 | 0.75 | ESR1 (0.42) | CHRM3RGS12KIF11ESR1CHRM2 | |
| SCHEMBL2390819 | 0.75 | RGS12 (0.43) | CHRM3RGS12KIF11ESR1SMN1; SMN2 | |
| SCHEMBL2390466 | 0.75 | RGS12 (0.43) | CHRM3RGS12KIF11ESR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152109-C | Arylheterocycle substituted dibenzofuranpyran-type photochromic compound and its preparing process and usage | 中国科学院感光化学研究所 | 2004-06-02 | — | — | CN | disclosed |
| CN-1152108-C | Arylheterocycle substituted naphthopyran-type photochromic compound and its preparing process and usage | 中国科学院感光化学研究所 | 2004-06-02 | — | — | CN | disclosed |
| CN-1328108-A | Arylheterocycle substituted naphthopyran-type photochromic compound and its preparing process and usage | INST PHOTOSENSITIVE CHEMISTRY CAS (CN) | 2001-12-26 | — | — | CN | disclosed |
| CN-1328109-A | Arylheterocycle substituted dibenzofuranpyran-type photochromic compound and its preparing process and usage | INST PHOTOSENSITIVE CHEMISTRY CAS (CN) | 2001-12-26 | — | — | CN | disclosed |