Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19479269 | 0.85 | ALDH1A1 (0.39) | HTR6TSHRNUDT1 | |
| SCHEMBL29123203 | 0.76 | PRKCI (0.36) | TSHRPRKCICA12CA1CA2 | |
| SCHEMBL27896850 | 0.75 | HTR6 (0.36) | HTR6PRKCI | |
| SCHEMBL27461874 | 0.74 | TSHR (0.35) | HTR6TSHR | |
| SCHEMBL9876231 | 0.74 | TSHR (0.35) | HTR6TSHRNUDT1 | |
| SCHEMBL10965241 | 0.72 | ALDH1A1 (0.34) | HTR6TSHR | |
| SCHEMBL27792500 | 0.72 | TSHR (0.33) | HTR6TSHR | |
| SCHEMBL27276200 | 0.72 | PRKCI (0.33) | PRKCI | |
| SCHEMBL28169413 | 0.72 | ALDH1A1 (0.52) | HTR6TSHRNUDT1CA12CA1 | |
| SCHEMBL27583259 | 0.72 | TSHR (0.33) | HTR6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1157386-C | Trisubstituted 1,3,5-triazine derivatives for treatment by HIV infections | ղɭҩҵ����˾ | 2004-07-14 | — | — | CN | disclosed |
| CN-1395566-A | Corticotropin releasing factor antagonists | PFIZER PROD INC (US) | 2003-02-05 | — | — | CN | disclosed |
| CN-1295566-A | Trisubstituted 1,3,5-triazine derivatives for treatment by HIV infections | JANSSEN PHARMACEUTICA NV (BE) | 2001-05-16 | — | — | CN | disclosed |