Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876231 | 0.74 | TSHR (0.35) | TSHRHTR6 | |
| SCHEMBL27461874 | 0.74 | TSHR (0.35) | TSHRHTR6 | |
| SCHEMBL27464483 | 0.72 | HTR6 (0.36) | TSHRHTR6 | |
| SCHEMBL10965241 | 0.72 | ALDH1A1 (0.34) | TSHRHTR6 | |
| SCHEMBL27792500 | 0.72 | TSHR (0.33) | TSHRHTR6 | |
| SCHEMBL1783525 | 0.71 | TSHR (0.47) | TSHRHTR6 | |
| SCHEMBL27598979 | 0.70 | AOC1 (0.42) | — | |
| Iodide SCHEMBL31463955 | 0.68 | TSHR (0.44) | TSHRHTR6 | |
| SCHEMBL5515978 | 0.67 | RAPGEF4 (0.36) | — | |
| SCHEMBL27903534 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101925578-B | 6-substituted-thio-2-amino-quinoline derivatives useful as inhibitors of ss-secretase (BACE) | JANSSEN PHARMACEUTICA NV | 2012-11-28 | — | — | CN | claimed |
| CN-101925578-A | 6-substituted-thio-2-amino-quinoline derivatives useful as inhibitors of ss-secretase (BACE) | JANSSEN PHARMACEUTICA NV | 2010-12-22 | — | — | CN | claimed |
| CN-101035772-A | 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2007-09-12 | — | — | CN | claimed |
| CN-1370176-A | Subsstituted heterocycle fused gamma-carbolines | BRISTOL MYERS SQUIBB CO (US) | 2002-09-18 | — | — | CN | claimed |
| CN-1370169-A | Substituted heterocycle fused gamma-carbolines | BRITOL MYERS SQUIBB CO (US) | 2002-09-18 | — | — | CN | claimed |
| CN-101979394-B | A method to inhibit ethylene responses in plants | ROHM & HAAS | 2013-04-03 | — | — | CN | disclosed |
| CN-101925578-B | 6-substituted-thio-2-amino-quinoline derivatives useful as inhibitors of ss-secretase (BACE) | JANSSEN PHARMACEUTICA NV | 2012-11-28 | — | — | CN | disclosed |
| CN-101979394-A | A method to inhibit ethylene responses in plants | ROHM & HAAS | 2011-02-23 | — | — | CN | disclosed |
| CN-101035770-B | 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA NV | 2011-02-23 | — | — | CN | disclosed |
| CN-101925578-A | 6-substituted-thio-2-amino-quinoline derivatives useful as inhibitors of ss-secretase (BACE) | JANSSEN PHARMACEUTICA NV | 2010-12-22 | — | — | CN | disclosed |
| CN-101035772-A | 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2007-09-12 | — | — | CN | disclosed |
| CN-101035770-A | Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2007-09-12 | — | — | CN | disclosed |
| CN-101035771-A | 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2007-09-12 | — | — | CN | disclosed |
| CN-1463263-A | Method for inhibiting ethylene response in plants | ROHM & HAAS (US) | 2003-12-24 | — | — | CN | disclosed |
| CN-1370169-A | Substituted heterocycle fused gamma-carbolines | BRITOL MYERS SQUIBB CO (US) | 2002-09-18 | — | — | CN | disclosed |
| CN-1370176-A | Subsstituted heterocycle fused gamma-carbolines | BRISTOL MYERS SQUIBB CO (US) | 2002-09-18 | — | — | CN | disclosed |