Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | MME | P08473 | 7/20 | 0.54 |
| ▸ | ACE | P12821 | 7/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FCER2 | P06734 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017170 | 0.95 | MME (0.61) | TACR1MMEACECTSLCTSB | |
| SCHEMBL27444764 | 0.92 | HDAC1 (0.50) | TACR1MMEACECTSLCTSB | |
| SCHEMBL27464504 | 0.89 | ACE (0.60) | TACR1MMEACECTSLCTSB | |
| SCHEMBL27462736 | 0.88 | TACR1 (0.55) | TACR1MMEACECTSLCTSB | |
| SCHEMBL8450193 | 0.87 | TACR1 (0.52) | TACR1MMEACECTSLCTSB | |
| SCHEMBL8028778 | 0.87 | MME (0.52) | MMEACE | |
| SCHEMBL27446786 | 0.87 | ACE (0.51) | TACR1MMEACECTSLCTSB | |
| SCHEMBL8027188 | 0.84 | ACE (0.67) | TACR1MMEACECTSLCTSB | |
| SCHEMBL8027264 | 0.84 | ACE (0.74) | MMEACEMMP9MMP8 | |
| SCHEMBL8030684 | 0.83 | MME (0.62) | TACR1MMEACECTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |