Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 18/20 | 0.46 |
| ▸ | HTR2A | P28223 | 18/20 | 0.46 |
| ▸ | DRD3 | P35462 | 18/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL27483381 | 0.86 | HTR1A (0.51) | HTR1A | |
| SCHEMBL12081257 | 0.83 | HTR2C (0.47) | MGAMAMY1AGAASIMGAM2 | |
| Methyl Alcohol SCHEMBL27462714 | 0.79 | HTR1A (0.54) | HTR1A | |
| SCHEMBL9715368 | 0.77 | EED (0.51) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8485229 | 0.75 | MGAM (0.43) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL1781998 | 0.75 | TP53 (0.47) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL6782222 | 0.74 | ABCG2 (0.43) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL13584700 | 0.73 | ABCG2 (0.46) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL28784844 | 0.73 | MGAM (0.44) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL24326967 | 0.71 | MAPT (0.49) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152679-C | Melatonergic agents of benzodioxoles, benzofurans, dihydrobenzofurans and benzodioxanes | ����˹�ж�-����˹˹������˾ | 2004-06-09 | — | — | CN | disclosed |
| CN-1239886-A | Benzodioxole, benzofuran, dihydrobenzofuran, and benzodioxane melatonergic agent | BRISTOL MYERS SQUIBB CO (US) | 1999-12-29 | — | — | CN | disclosed |