Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 9/20 | 0.36 |
| ▸ | HTR2A | P28223 | 9/20 | 0.36 |
| ▸ | DRD3 | P35462 | 9/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488320 | 0.86 | DRD2 (0.41) | PTGS1PTGS2DRD2 | |
| SCHEMBL8485225 | 0.82 | ABCG2 (0.40) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL6679351 | 0.78 | HTR2C (0.51) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL6679348 | 0.78 | HTR2C (0.51) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL6677212 | 0.77 | MGAM (0.40) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL6677215 | 0.77 | MGAM (0.40) | MGAMAMY1AGAASIMGAM2 | |
| Methylamine SCHEMBL27464902 | 0.75 | MGAM (0.49) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL6782222 | 0.74 | ABCG2 (0.43) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8486172 | 0.74 | MGAM (0.43) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL13584700 | 0.73 | ABCG2 (0.46) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |