Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423799 | 0.81 | EGFR (0.50) | — | |
| SCHEMBL9017772 | 0.81 | ATM (0.42) | ALDH1A1HPGDHTTATMMAPT | |
| SCHEMBL5322452 | 0.79 | MAPT (0.57) | ALDH1A1HPGDHTTMAPTGAA | |
| SCHEMBL1545701 | 0.79 | PKM (0.52) | ALDH1A1HPGDHTTMAPTGAA | |
| SCHEMBL27907766 | 0.79 | CA12 (0.58) | ALDH1A1HPGDHTTATMMAPT | |
| SCHEMBL2991009 | 0.79 | CA12 (0.58) | ALDH1A1HPGDHTTATMMAPT | |
| SCHEMBL30389755 | 0.79 | CA12 (0.58) | ALDH1A1HPGDHTTATMMAPT | |
| SCHEMBL13973960 | 0.77 | ATM (0.42) | ALDH1A1HPGDHTTATMMAPT | |
| SCHEMBL5186624 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDHTTATMMAPT | |
| SCHEMBL2856590 | 0.76 | HTT (0.68) | ALDH1A1HPGDHTTATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1143675-C | Heteroarylpiperidines, pyrrolidines and piprazines and their use as antipsychotics and analgetics | ���µ�˹ҩ�﹫˾ | 2004-03-31 | — | — | CN | disclosed |
| CN-1136275-A | Arylheterocyclylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics | HOECHST ROUSSEL PHARMA (US) | 1996-11-20 | — | — | CN | disclosed |