SCHEMBL9423799

SCHEMBL9423799

CN(C)CCC(=O)c1ccc(O)c(N(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.50
GSR P00390 2/20 0.50
THRA P10827 14/20 0.49
THRB P10828 12/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17549644 0.82 THRA (0.56) EGFRGSRTHRATHRB
SCHEMBL27464962 0.81 ALDH1A1 (0.50)
Hydrochloric Acid SCHEMBL3324195 0.81 THRA (0.54) EGFRGSRTHRATHRB
SCHEMBL9509983 0.78 GSR (0.72) EGFRGSRTHRATHRB
SCHEMBL17551934 0.78 THRA (0.61) EGFRTHRATHRB
Hydrochloric Acid SCHEMBL10353476 0.77 GSR (0.73) EGFRGSRTHRATHRB
SCHEMBL9509517 0.75 THRA (0.60) EGFRGSRTHRATHRB
SCHEMBL1545701 0.75 PKM (0.52)
SCHEMBL5322452 0.75 MAPT (0.57)
SCHEMBL11270329 0.75 GSR (0.64) EGFRGSRTHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5308840-A Antioxidants, antiallergens and antiinflammatory agents GREEN CROSS CORPORATION (JP) 1994-05-03 US disclosed
EP-0508334-A2 Novel aminophenol derivatives and pharmaceutical compositions thereof THE GREEN CROSS CORPORATION (JP) 1992-10-14 EP disclosed